UBGEN
SPECIALISTS OF BONE SURGERY IN DENTISTRY
Earth: a grain of sand in a vast cosmic arena. To date, the only known world capable of sustaining life. Everyone we love and every person who has ever lived has spent their life here. This is where we are. This is our home. This is who we are. That is why we decided to dedicate our professional lives to improving the lives of others. To achieve this, we have followed difficult and risky paths. Indeed, many consider it impossible. We were aware that failures would outnumber successes. But life is worth living only if we realize our uniqueness by kindly caring for one another. In this approach, each of us has one primary mission, and only one: to fulfill our potential in harmony with our environment.
A comprehensive range of tissue regeneration solutions that address the diverse needs of bone regenerative surgery.
CHOOSING UBGEN
Made in Italy with CE marking
Comprehensive redesign
Given that hydroxyapatite has the same composition as human bone and that an organic matrix forms after a short period of time, the body recognizes RE-BONE® as a material that is not foreign to it, and therefore can initiate the formation of natural bone, its resorption, and its remodeling. Osteoclasts resorb the granules, while at the same time osteoblasts form bone. During this process, RE-BONE® is completely replaced by bone, thereby preventing the effects of foreign substances. Cell viability
Συγκρίνοντας τη ζωτικότητα των κυττάρων των οστεοβλαστών του RE-BONE® με άλλες εταιρείες, μπορούμε να παρατηρήσουμε μεγαλύτερο ποσοστό επιβίωσης των κυττάρων που αντιστοιχεί στο 96%, αντί για το 90% του άλλου δείγματος της σύγκρισης.
Osteogenic capacity
RE-BONE® retains most of the proteins in the cellular matrix, which are important for the regeneration of the surrounding tissue. Experiments with adipose-derived stem cells (ADSCs) demonstrate that RE-BONE® can induce the expression of specific bone markers (osteopontin, osteocalcin, osteonectin, and type I collagen), the combined expression of which characterizes bone tissue as early as 21 days.
Microporous material for reducing the resorption time of bone substitute
An analysis was performed using a scanning electron microscope (SEM), and the images obtained show micro-roughness, intergranular cracking, which allows blood vessels and cells to colonize the graft, thereby reducing resorption time.
Χαρακτηριστικά:
The only material made from 100% Italian-made chain
It comes exclusively from the femoral epiphysis of cattle
Decellularized and deproteinized using a unique
procedure
Developed in collaboration with the Department of Biomedical Sciences
Faculty of Sciences, University of Padua
Sequence: thermal shock – chemical wash / Y Rays
Store at room temperature between 5°C and 30°C
CE Marking. Italian Ministry of Health Certifications
Advantages:
Biocompatible and nanostructured
Similar to the cellular matrix of human bone, it promotes
cell adhesion, proliferation, and differentiation
It promotes neovascularization by preserving proteins
of the extracellular matrix
Volumetrically stable
Reduced reabsorption time
RE-BONE® allows cells and blood vessels to
settle in more quickly
Rough surface: excellent cell adhesion and
blood absorption
